Pills

Pills are pickups that can provide useful or inhibiting effects. They take up the same slot as cards and runes.

At the start of each run, an effect is randomly assigned to each color of pill. The pill effect for that color will remain constant throughout the run. (However, it is possible for PHD or Virgo to reassign some of the effects, such that 2 different colored pills will have the same effect.) The set of pill effects for any given run is usually known as the pill pool.

Lunatic Mod's custom pills are currently unreleased, but are expected to be added in upcoming updates.

Pill Appearances




Strategy

 * Use of unidentified pills is recommended for outside of combat as Confusion!, Hematocheria, I'm Dizzy..., Macropsia, and Overdose! can be detrimental mid-fight. However, Asbestos, Nasty Gas, and Projectile Vomiting are nearly useless outside of combat.