Pupula Duplex

Pupula Duplex is a passive item added in the Afterbirth DLC.

Effects

 * Widens Isaac's tears, increasing their hitbox.
 * Grants spectral tears.

Interactions

 * 8 Inch Nails: Overridden by Pupula Duplex.
 * Brimstone: Overrides Pupula Duplex.
 * Death's Touch: Greatly increases the size of Isaac's scythes.
 * Dr. Fetus: Single spectral bomb.
 * Head Of The Keeper: Greatly increases the size of Isaac's coin tears.
 * The Ludovico Technique: Tears do not increase in size an additional amount.
 * Mom's Knife: Overrides Pupula Duplex.
 * Polyphemus: Greatly increases shot size and damage.
 * Tech X: Overrides Pupula Duplex.
 * Tough Love: Greatly increases the size of the tooth shot.

Seeds
HN4T QMN7 (First floor treasure room) HLTD B7WD (Treasure room adjacent to spawn) XVA6 BQFC (First floor treasure room)

Trivia

 * “Pupula Duplex” is said to be a rare condition in which a person has two irises and two pupils in one eye. There have never been any recorded cases however.