Number One

Number One is a passive item.

Effect

 * Range is heavily decreased, but the fire rate is majorly increased.
 * Tears turn yellow and are fired from Isaac's lower body rather than his head.

Interactions

 * Azazel - Lowers range, reduces charge time.
 * Mom's Knife - The knife turns yellow and the maximum range is significantly reduced.
 * Toothpicks - Tears become orange.
 * Marked - Tears become orange. Firing rate is increased, Marked's effect is unaffected but range is reduced.

Synergies

 * Brimstone - The laser turns yellow and charges at a much faster rate with no decrease to range.
 * Technology - The laser turns yellow and Technology's firing rate is greatly increased with no decrease to range.
 * Incubus - The Incubus fires at a much faster rate with no decrease to range.

Trivia

 * "Number One" is a euphemism for urination.
 * In the original Binding of Isaac, Number One had the effect of turning all future Range Down pills into Range Up pills. This was presumably designed to reduce the risk of players being stuck in situations where their range would become too low to clear certain rooms. However, in Rebirth, Number One no longer has this effect, and will not turn Range Down pills into Range Up pills.
 * This item is used in Challenge #2 (High Brow).

Seeds
J172 PRAK (Treasure room adjacent to spawn) VMA3 SMZA (Treasure room adjacent to spawn) SRX8 FXHM (Treasure room adjacent to spawn) (XL floor) (Hard mode only) 0RJ7 VQYY (First floor treasure room) WYH4 A4DX (First floor treasure room)