A Card Against Humanity

A Card Against Humanity is a special card.

Effects

 * Fills the room with poop.

Synergies

 * Midas' Touch - Spawned poops have a great chance to turn into golden poops.
 * Petrified Poop - Greatly increases the chance of finding a pickup when destroying poop.
 * Leo / Thunder Thighs / The Nail - Allows all the poop to be easily destroyed.
 * Infested! Pill - Every pile of poop spawns a blue spider.
 * Lil Larva - Every pile of poop spawns a blue Fly.

Interactions

 * Brown Cap - All the poop explodes in a chain reaction once one is destroyed.
 * Dr. Fetus / Ipecac - If Isaac has no other means of destroying poop than his explosive tears, he will have to hurt himself to clear out a path through the poop unless he has acquired Pyromaniac or Host Hat.

Trivia

 * The item is a reference to Cards Against Humanity, a satirical card game whose name in turn references "crimes against humanity". Specifically, it refers to the way the first player is chosen: Whoever was the last to poop goes first.
 * In the pop-up (if not disabled) for unlocking this card, the text on it reads "A room full of poop".
 * This actually contradicts the original card game, as black cards are prompts while the white cards are answers to the prompt.

A Card Against Humanity