Large Zit

Large Zit is a passive item added in Afterbirth †.

Effects

 * Adds a chance to fire a creep shot that deals double damage and leaves a trail of white creep that slows enemies.

Synergies

 * Ipecac: High base damage from Ipecac is doubled, causing very powerful creep shots.

Interactions

 * Dr. Fetus: Isaac occasionally fires a tear along with a bomb, which has the slowing effect and creep trail.
 * Marked: Creep shots are fired only while fire keys are actively pressed, and in the direction of the keys instead of the targeting crosshair.
 * Brimstone: Creep shots will still be fired occasionally while holding the fire button.

Seeds
SPPL ZKGR (Treasure Room adjacent to spawn)

Large Zit